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Transcriptional plasticity drives leukemia immune escape

Transcriptional plasticity drives leukemia immune escape

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2563942176

Transcriptional plasticity drives leukemia immune escape

About this item

Full title

Transcriptional plasticity drives leukemia immune escape

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-08

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Relapse of acute myeloid leukemia (AML) after allogeneic bone marrow transplantation (alloSCT) has been linked to immune evasion due to reduced expression of major histocompatibility complex class II (MHC-II) proteins through unknown mechanisms. We developed CORENODE, a computational algorithm for genome-wide transcription network decomposition, th...

Alternative Titles

Full title

Transcriptional plasticity drives leukemia immune escape

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2563942176

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2563942176

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.08.23.457351