Neprilysin-sensitive amyloidogenic Aβ versus IDE-sensitive soluble Aβ: a probable mechanistic cause...
Neprilysin-sensitive amyloidogenic Aβ versus IDE-sensitive soluble Aβ: a probable mechanistic cause for sporadic Alzheimer's disease
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Neprilysin (NEP) and insulin-degrading enzyme (IDE) are considered the two major catabolic enzymes that degrade amyloid beta peptide (Abeta), the primary cause of Alzheimer's disease (AD). However, their roles in Abeta metabolism in vivo have never been compared in an impartial and side-by-side manner. Here, we crossbred single App knock-in mice wi...
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Full title
Neprilysin-sensitive amyloidogenic Aβ versus IDE-sensitive soluble Aβ: a probable mechanistic cause for sporadic Alzheimer's disease
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TN_cdi_proquest_journals_2563943353
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2563943353
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E-ISSN
2692-8205
DOI
10.1101/2021.08.22.457281
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https://www.proquest.com/docview/2563943353?pq-origsite=primo&accountid=13902
