Sequence grammar underlying unfolding and phase separation of globular proteins
Sequence grammar underlying unfolding and phase separation of globular proteins
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Aberrant phase separation of globular proteins is associated with many diseases. Here, we use a model protein system to understand how unfolded states of globular proteins drive phase separation and the formation of unfolded protein deposits (UPODs). For UPODs to form, the concentrations of unfolded molecules must be above a threshold value. Additi...
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Full title
Sequence grammar underlying unfolding and phase separation of globular proteins
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TN_cdi_proquest_journals_2564148103
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2564148103
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E-ISSN
2692-8205
DOI
10.1101/2021.08.20.457073
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https://www.proquest.com/docview/2564148103?pq-origsite=primo&accountid=13902