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Mild hyperhomocysteinemia induces blood–brain barrier dysfunction but not neuroinflammation in the c...

Mild hyperhomocysteinemia induces blood–brain barrier dysfunction but not neuroinflammation in the c...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2564815041

Mild hyperhomocysteinemia induces blood–brain barrier dysfunction but not neuroinflammation in the cerebral cortex and hippocampus of wild-type mice

About this item

Full title

Mild hyperhomocysteinemia induces blood–brain barrier dysfunction but not neuroinflammation in the cerebral cortex and hippocampus of wild-type mice

Publisher

1840 Woodward Drive, Suite 1, Ottawa, ON K2C 0P7: NRC Research Press

Journal title

Canadian journal of physiology and pharmacology, 2021-09, Vol.99 (9), p.847-856

Language

English

Formats

Publication information

Publisher

1840 Woodward Drive, Suite 1, Ottawa, ON K2C 0P7: NRC Research Press

More information

Scope and Contents

Contents

This study explored the potential effects of mild hyperhomocysteinemia (HHcy) on the blood–brain barrier (BBB) and neuroinflammation. Seven-week-old male wild-type C57BL/6 mice were fed normal mouse chow (the control group) or a methionine-enriched diet (the HHcy group) for 14 weeks. Mice in the HHcy group exhibited a slight increase in serum Hcy l...

Alternative Titles

Full title

Mild hyperhomocysteinemia induces blood–brain barrier dysfunction but not neuroinflammation in the cerebral cortex and hippocampus of wild-type mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2564815041

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2564815041

Other Identifiers

ISSN

0008-4212

E-ISSN

1205-7541

DOI

10.1139/cjpp-2020-0507

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