Ligand binding at the protein–lipid interface: strategic considerations for drug design
Ligand binding at the protein–lipid interface: strategic considerations for drug design
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Many drug targets are embedded within the phospholipid bilayer of cellular membranes, including G protein-coupled receptors, ion channels, transporters and membrane-bound enzymes. Increasing evidence from biophysical and structural studies suggests that many small-molecule drugs commonly associate with these targets at binding sites at the protein–...
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Full title
Ligand binding at the protein–lipid interface: strategic considerations for drug design
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TN_cdi_proquest_journals_2567801523
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2567801523
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ISSN
1474-1776
E-ISSN
1474-1784
DOI
10.1038/s41573-021-00240-2
