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A network-based approach to integrate nutrient environment in the prediction of synthetic lethality...

A network-based approach to integrate nutrient environment in the prediction of synthetic lethality...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2568824626

A network-based approach to integrate nutrient environment in the prediction of synthetic lethality in cancer metabolism

About this item

Full title

A network-based approach to integrate nutrient environment in the prediction of synthetic lethality in cancer metabolism

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-09

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Synthetic Lethality (SL) is a promising concept in cancer research. A number of computational methods have been developed to predict SL in cancer metabolism, among which our network-based computational approach, based on genetic Minimal Cut Sets (gMCSs), can be found. A major challenge of these approaches to SL is to systematically consider tumor e...

Alternative Titles

Full title

A network-based approach to integrate nutrient environment in the prediction of synthetic lethality in cancer metabolism

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2568824626

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2568824626

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.09.01.458495