IRE1α drives lung epithelial progenitor dysfunction to establish a niche for pulmonary fibrosis
IRE1α drives lung epithelial progenitor dysfunction to establish a niche for pulmonary fibrosis
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Idiopathic pulmonary fibrosis (IPF) is a disease of progressive interstitial fibrosis, which leads to severe debilitation, respiratory failure, and death. In IPF, environmental exposures interact with genetic risk factors to engender critical patho-etiological events in lung epithelial cells, including endoplasmic reticulum (ER) stress and TGFβ sig...
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Full title
IRE1α drives lung epithelial progenitor dysfunction to establish a niche for pulmonary fibrosis
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TN_cdi_proquest_journals_2573639101
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2573639101
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E-ISSN
2692-8205
DOI
10.1101/2021.09.16.460705
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https://www.proquest.com/docview/2573639101?pq-origsite=primo&accountid=13902
