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Deletion or inhibition of astrocytic transglutaminase 2 promotes functional recovery after spinal co...

Deletion or inhibition of astrocytic transglutaminase 2 promotes functional recovery after spinal co...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2573640979

Deletion or inhibition of astrocytic transglutaminase 2 promotes functional recovery after spinal cord injury

About this item

Full title

Deletion or inhibition of astrocytic transglutaminase 2 promotes functional recovery after spinal cord injury

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-09

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Following CNS injury astrocytes become reactive and exhibit pro-regenerative or harmful properties. However, the molecular mechanisms that cause astrocytes to adopt either phenotype are not well understood. Transglutaminase 2 (TG2) plays a key role in regulating the response of astrocytes to insults. Here we used mice in which TG2 was specifically...

Alternative Titles

Full title

Deletion or inhibition of astrocytic transglutaminase 2 promotes functional recovery after spinal cord injury

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2573640979

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2573640979

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.09.15.460455