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Combi-Seq: Multiplexed transcriptome-based profiling of drug combinations using 1 deterministic barc...

Combi-Seq: Multiplexed transcriptome-based profiling of drug combinations using 1 deterministic barc...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2573643642

Combi-Seq: Multiplexed transcriptome-based profiling of drug combinations using 1 deterministic barcoding in single-cell droplets

About this item

Full title

Combi-Seq: Multiplexed transcriptome-based profiling of drug combinations using 1 deterministic barcoding in single-cell droplets

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-09

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Anti-cancer therapies often exhibit only short-term effects. Tumors typically develop drug resistance causing relapses that might be tackled with drug combinations. Identification of the right combination is challenging and would benefit from high-content, high-throughput combinatorial screens directly on patient biopsies. However, such screens req...

Alternative Titles

Full title

Combi-Seq: Multiplexed transcriptome-based profiling of drug combinations using 1 deterministic barcoding in single-cell droplets

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2573643642

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2573643642

Other Identifiers

DOI

10.1101/2021.09.16.460212