Fragile X syndrome patient-derived neurons developing in the mouse brain show FMR1 -dependent phenot...
Fragile X syndrome patient-derived neurons developing in the mouse brain show FMR1 -dependent phenotypes
About this item
Full title
Author / Creator
Krzisch, Marine A , Wu, Hao A , Yuan, Bingbing , Whitfield, Troy W , Liu, X Shawn , Fu, Dongdong , Shih, Jennifer , Garrett-Engele, Carrie M , Chang, Aaron N , Warren, Stephen , Cacace, Angela , Andrykovich, Kristin A , Rietjens, Rosalie G J , Jain, Bhav , Wallace, Owen , Sur, Mriganka and Jaenisch, Rudolph
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
Formats
Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Subjects
More information
Scope and Contents
Contents
Abnormal neuronal development in Fragile X syndrome (FXS) is poorly understood. Data on FXS patients remain scarce and FXS animal models have failed to yield successful therapies. In vitro models do not fully recapitulate the morphology and function of human neurons. Here, we co-injected neural precursor cells (NPCs) from FXS patient-derived and co...
Alternative Titles
Full title
Fragile X syndrome patient-derived neurons developing in the mouse brain show FMR1 -dependent phenotypes
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2577220050
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2577220050
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2021.09.27.461739
How to access this item
https://www.proquest.com/docview/2577220050?pq-origsite=primo&accountid=13902
