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Hyaluronidase-1-mediated glycocalyx impairment underlies endothelial abnormalities in polypoidal cho...

Hyaluronidase-1-mediated glycocalyx impairment underlies endothelial abnormalities in polypoidal cho...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2579877249

Hyaluronidase-1-mediated glycocalyx impairment underlies endothelial abnormalities in polypoidal choroidal vasculopathy

About this item

Full title

Hyaluronidase-1-mediated glycocalyx impairment underlies endothelial abnormalities in polypoidal choroidal vasculopathy

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-10

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Background: Polypoidal choroidal vasculopathy (PCV), a subtype of age-related macular degeneration (AMD), is characterized by polyp-like dilatation of blood vessels and turbulent blood flow in the choroid of the eye. Gold standard anti-vascular endothelial growth factor (anti-VEGF) therapy often fails to regress polypoidal lesions in patients. Curr...

Alternative Titles

Full title

Hyaluronidase-1-mediated glycocalyx impairment underlies endothelial abnormalities in polypoidal choroidal vasculopathy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2579877249

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2579877249

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.10.06.463357