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Whole genome sequence analysis of blood lipid levels in >66,000 individuals

Whole genome sequence analysis of blood lipid levels in >66,000 individuals

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2581101671

Whole genome sequence analysis of blood lipid levels in >66,000 individuals

About this item

Full title

Whole genome sequence analysis of blood lipid levels in >66,000 individuals

Author / Creator

Margaret Sunitha Selvaraj , Li, Xihao , Li, Zilin , Pampana, Akhil , Zhang, David Y , Park, Joseph , Aslibekyan, Stella , Bis, Joshua C , Brody, Jennifer A , Cade, Brian E , Lee-Ming, Chuang , Ren-Hua, Chung , Curran, Joanne E , De Las Fuentes, Lisa , De Vries, Paul S , Duggirala, Ravindranath , Freedman, Barry I , Graff, Mariaelisa , Guo, Xiuqing , Heard-Costa, Nancy , Hidalgo, Bertha , Chii-Min Hwu , Irvin, Marguerite R , Kelly, Tanika N , Kral, Brian G , Lange, Leslie , Li, Xiaohui , Martin, Lisa , Lubitz, Steven A , Manichaikul, Ani W , Preuss, Michael , Montasser, May E , Morrison, Alanna C , Take Naseri , O'connell, Jeffrey R , Palmer, Nicholette D , Peyser, Patricia A , Reupena, Muagututia S , Smith, Jennifer A , Sun, Xiao , Taylor, Kent D , Tracy, Russell P , Tsai, Michael Y , Wang, Zhe , Wang, Yuxuan , Bao, Wei , Wilkins, John T , Yanek, Lisa R , Zhao, Wei , Arnett, Donna K , Blangero, John , Boerwinkle, Eric , Bowden, Donald W , Chen, Yii-Der Ida , Correa, Adolfo , Cupples, L Adrienne , Dutcher, Susan K , Ellinor, Patrick T , nage, Myriam , Gabriel, Stacey , Germer, Soren , Gibbs, Richard , He, Jiang , Kaplan, Robert C , Kardia, Sharon Lr , Kim, Ryan , Kooperberg, Charles , Loos, Ruth Jf , Martinez, Karine , Mathias, Rasika A , Mcgarvey, Stephen T , Mitchell, Braxton D , Nickerson, Deborah , North, Kari E , Psaty, Bruce M , Redline, Susan , Reiner, Alexander P , Vasan, Ramachandran S , Rich, Stephen S , Willer, Cristen , Rotter, Jerome I , Rader, Daniel J , Lin, Xihong , Nhlbi Trans-Omics For Precision Medicine (Topmed) Consortium , Peloso, Gina M and Natarajan, Pradeep

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-10

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Plasma lipids are heritable modifiable causal factors for coronary artery disease, the leading cause of death globally. Despite the well-described monogenic and polygenic bases of dyslipidemia, limitations remain in discovery of lipid-associated alleles using whole genome sequencing, partly due to limited sample sizes, ancestral diversity, and inte...

Alternative Titles

Full title

Whole genome sequence analysis of blood lipid levels in >66,000 individuals

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2581101671

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2581101671

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.10.11.463514