Direct induction of human neurons from fibroblasts carrying the neuropsychiatric 22q11.2 microdeleti...
Direct induction of human neurons from fibroblasts carrying the neuropsychiatric 22q11.2 microdeletion reveals transcriptome- and epigenome-wide alterations
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Standard methods for the creation of neuronal cells via direct induction from primary tissue use perinatal fibroblasts, which hinders the important study of patient specific genetic lesions such as those underlying neuropsychiatric disorders. To address this we developed a novel method for the direct induction of neuronal cells (induced neuronal ce...
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Full title
Direct induction of human neurons from fibroblasts carrying the neuropsychiatric 22q11.2 microdeletion reveals transcriptome- and epigenome-wide alterations
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TN_cdi_proquest_journals_2581960410
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2581960410
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E-ISSN
2692-8205
DOI
10.1101/2021.10.14.464344
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https://www.proquest.com/docview/2581960410?pq-origsite=primo&accountid=13902
