ACC inhibitor alone or co-administered with a DGAT2 inhibitor in patients with non-alcoholic fatty l...
ACC inhibitor alone or co-administered with a DGAT2 inhibitor in patients with non-alcoholic fatty liver disease: two parallel, placebo-controlled, randomized phase 2a trials
About this item
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Author / Creator
Calle, Roberto A. , Amin, Neeta B. , Carvajal-Gonzalez, Santos , Ross, Trenton T. , Bergman, Arthur , Aggarwal, Sudeepta , Crowley, Collin , Rinaldi, Anthony , Mancuso, Jessica , Aggarwal, Naresh , Somayaji, Veena , Inglot, Malgorzata , Tuthill, Theresa A. , Kou, Kou , Boucher, Magalie , Tesz, Greg , Dullea, Robert , Bence, Kendra K. , Kim, Albert M. , Pfefferkorn, Jeffrey A. and Esler, William P.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Alterations in lipid metabolism might contribute to the pathogenesis of non-alcoholic fatty liver disease (NAFLD). However, no pharmacological agents are currently approved in the United States or the European Union for the treatment of NAFLD. Two parallel phase 2a studies investigated the effects of liver-directed ACC1/2 inhibition in adults with...
Alternative Titles
Full title
ACC inhibitor alone or co-administered with a DGAT2 inhibitor in patients with non-alcoholic fatty liver disease: two parallel, placebo-controlled, randomized phase 2a trials
Authors, Artists and Contributors
Author / Creator
Amin, Neeta B.
Carvajal-Gonzalez, Santos
Ross, Trenton T.
Bergman, Arthur
Aggarwal, Sudeepta
Crowley, Collin
Rinaldi, Anthony
Mancuso, Jessica
Aggarwal, Naresh
Somayaji, Veena
Inglot, Malgorzata
Tuthill, Theresa A.
Kou, Kou
Boucher, Magalie
Tesz, Greg
Dullea, Robert
Bence, Kendra K.
Kim, Albert M.
Pfefferkorn, Jeffrey A.
Esler, William P.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2581965856
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2581965856
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-021-01489-1
