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New insight on the role of liraglutide in alleviating dexamethasone-induced pancreatic cytotoxicity...

New insight on the role of liraglutide in alleviating dexamethasone-induced pancreatic cytotoxicity...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2593567253

New insight on the role of liraglutide in alleviating dexamethasone-induced pancreatic cytotoxicity via improving redox status, autophagy flux, and PI3K/Akt/Nrf2 signaling

About this item

Full title

New insight on the role of liraglutide in alleviating dexamethasone-induced pancreatic cytotoxicity via improving redox status, autophagy flux, and PI3K/Akt/Nrf2 signaling

Publisher

1840 Woodward Drive, Suite 1, Ottawa, ON K2C 0P7: NRC Research Press

Journal title

Canadian journal of physiology and pharmacology, 2021-11, Vol.99 (11), p.1217-1225

Language

English

Formats

Publication information

Publisher

1840 Woodward Drive, Suite 1, Ottawa, ON K2C 0P7: NRC Research Press

More information

Scope and Contents

Contents

Chronic glucocorticoids therapy is commonly complicated by steroid diabetes, although the underlying mechanisms are still elusive. Liraglutide, a glucagon-like peptide-1, was initially found to induce glycemic control and recently it was found to have many pleotropic effects; however, its role in pancreas remains unknown. The present study aims to...

Alternative Titles

Full title

New insight on the role of liraglutide in alleviating dexamethasone-induced pancreatic cytotoxicity via improving redox status, autophagy flux, and PI3K/Akt/Nrf2 signaling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2593567253

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2593567253

Other Identifiers

ISSN

0008-4212

E-ISSN

1205-7541

DOI

10.1139/cjpp-2021-0183

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