Understanding and overcoming resistance to PARP inhibitors in cancer therapy
Understanding and overcoming resistance to PARP inhibitors in cancer therapy
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Developing novel targeted anticancer therapies is a major goal of current research. The use of poly(ADP-ribose) polymerase (PARP) inhibitors in patients with homologous recombination-deficient tumours provides one of the best examples of a targeted therapy that has been successfully translated into the clinic. The success of this approach has so fa...
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Full title
Understanding and overcoming resistance to PARP inhibitors in cancer therapy
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TN_cdi_proquest_journals_2598833658
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2598833658
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ISSN
1759-4774
E-ISSN
1759-4782
DOI
10.1038/s41571-021-00532-x
