Long-term decreased cannabinoid type-1 receptor activity restores specific neurological phenotypes i...
Long-term decreased cannabinoid type-1 receptor activity restores specific neurological phenotypes in the Ts65Dn mouse model of Down syndrome
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Intellectual disability is the most prevalent and limiting hallmark of Down syndrome (DS), without any pharmacological treatment available. Neurodegeneration and neuroinflammation are relevant neurological features of DS reaching to early development of Alzheimer s disease. Preclinical evidence suggests that the endocannabinoid system, an important...
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Full title
Long-term decreased cannabinoid type-1 receptor activity restores specific neurological phenotypes in the Ts65Dn mouse model of Down syndrome
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TN_cdi_proquest_journals_2600526004
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2600526004
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E-ISSN
2692-8205
DOI
10.1101/2021.11.22.469296
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https://www.proquest.com/docview/2600526004?pq-origsite=primo&accountid=13902
