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Systematic assessment of the accuracy of subunit counting in biomolecular complexes using automated...

Systematic assessment of the accuracy of subunit counting in biomolecular complexes using automated...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2600527579

Systematic assessment of the accuracy of subunit counting in biomolecular complexes using automated single molecule brightness analysis

About this item

Full title

Systematic assessment of the accuracy of subunit counting in biomolecular complexes using automated single molecule brightness analysis

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-11

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Analysis of single molecule brightness allows subunit counting of high-order oligomeric biomolecular complexes. Although the theory behind the method has been extensively assessed, systematic analysis of the experimental conditions required to accurately quantify the stoichiometry of biological complexes remains challenging. In this work, we develo...

Alternative Titles

Full title

Systematic assessment of the accuracy of subunit counting in biomolecular complexes using automated single molecule brightness analysis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2600527579

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2600527579

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.11.22.469513