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Gordonia hydrophobica Nitrile Hydratase for Amide Preparation from Nitriles

Gordonia hydrophobica Nitrile Hydratase for Amide Preparation from Nitriles

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2602018222

Gordonia hydrophobica Nitrile Hydratase for Amide Preparation from Nitriles

About this item

Full title

Gordonia hydrophobica Nitrile Hydratase for Amide Preparation from Nitriles

Publisher

Basel: MDPI AG

Journal title

Catalysts, 2021-11, Vol.11 (11), p.1287

Language

English

Formats

Publication information

Publisher

Basel: MDPI AG

More information

Scope and Contents

Contents

The active pharmaceutical ingredient levetiracetam has anticonvulsant properties and is used to treat epilepsies. Herein, we describe the enantioselective preparation of the levetiracetam precursor 2-(pyrrolidine-1-yl)butanamide by enzymatic dynamic kinetic resolution with a nitrile hydratase enzyme. A rare representative of the family of iron-depe...

Alternative Titles

Full title

Gordonia hydrophobica Nitrile Hydratase for Amide Preparation from Nitriles

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2602018222

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2602018222

Other Identifiers

ISSN

2073-4344

E-ISSN

2073-4344

DOI

10.3390/catal11111287

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