MSH2-deficient prostate tumours have a distinct immune response and clinical outcome compared to MSH...
MSH2-deficient prostate tumours have a distinct immune response and clinical outcome compared to MSH2-deficient colorectal or endometrial cancer
About this item
Full title
Author / Creator
McCoy, Patrick , Mangiola, Stefano , Macintyre, Geoff , Hutchinson, Ryan , Tran, Ben , Pope, Bernard , Georgeson, Peter , Hong, Matthew K. H. , Kurganovs, Natalie , Lunke, Sebastian , Clarkson, Michael J. , Cmero, Marek , Kerger, Michael , Stuchbery, Ryan , Chow, Ken , Haviv, Izhak , Ryan, Andrew , Costello, Anthony J. , Corcoran, Niall M. and Hovens, Christopher M.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Background
Recent publications have shown patients with defects in the DNA mismatch repair (MMR) pathway driven by either MSH2 or MSH6 loss experience a significant increase in the incidence of prostate cancer. Moreover, this increased incidence of prostate cancer is accompanied by rapid disease progression and poor clinical outcomes.
Methods...
Alternative Titles
Full title
MSH2-deficient prostate tumours have a distinct immune response and clinical outcome compared to MSH2-deficient colorectal or endometrial cancer
Authors, Artists and Contributors
Author / Creator
Mangiola, Stefano
Macintyre, Geoff
Hutchinson, Ryan
Tran, Ben
Pope, Bernard
Georgeson, Peter
Hong, Matthew K. H.
Kurganovs, Natalie
Lunke, Sebastian
Clarkson, Michael J.
Cmero, Marek
Kerger, Michael
Stuchbery, Ryan
Chow, Ken
Haviv, Izhak
Ryan, Andrew
Costello, Anthony J.
Corcoran, Niall M.
Hovens, Christopher M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2602347056
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2602347056
Other Identifiers
ISSN
1365-7852
E-ISSN
1476-5608
DOI
10.1038/s41391-021-00379-4
