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The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations...

The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2607474486

The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: the case of the spike A222V mutation

About this item

Full title

The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: the case of the spike A222V mutation

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2022-02

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

The S:A222V point mutation, within the G clade, was characteristic of the 20E (EU1) SARS-CoV-2 variant identified in Spain in early summer 2020. This mutation has now reappeared in the Delta subvariant AY.4.2, raising questions about its specific effect on viral infection. We report combined serological, functional, structural and computational stu...

Alternative Titles

Full title

The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: the case of the spike A222V mutation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2607474486

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2607474486

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.12.05.471263