Genuine Selective Caspase-2 Inhibition with new Irreversible Small Peptidomimetics
Genuine Selective Caspase-2 Inhibition with new Irreversible Small Peptidomimetics
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Caspase-2 (Casp2) is a promising therapeutic target in several human diseases including nonalcoholic steatohepatitis (NASH) and Alzheimer's disease (AD). However, the design of active-site-directed inhibitor selective to individual caspase family members is challenging because caspases have extremely similar active sites. Here we present new peptid...
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Full title
Genuine Selective Caspase-2 Inhibition with new Irreversible Small Peptidomimetics
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TN_cdi_proquest_journals_2610243930
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2610243930
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E-ISSN
2692-8205
DOI
10.1101/2021.12.13.472505
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https://www.proquest.com/docview/2610243930?pq-origsite=primo&accountid=13902
