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MERS-CoV endoribonuclease and accessory proteins jointly evade host innate immunity during infection...

MERS-CoV endoribonuclease and accessory proteins jointly evade host innate immunity during infection...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2612228392

MERS-CoV endoribonuclease and accessory proteins jointly evade host innate immunity during infection of lung and nasal epithelial cells

About this item

Full title

MERS-CoV endoribonuclease and accessory proteins jointly evade host innate immunity during infection of lung and nasal epithelial cells

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-12

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Middle East respiratory syndrome coronavirus (MERS CoV) emerged into humans in 2012, causing highly lethal respiratory disease. The severity of disease may be in part because MERS CoV is adept at antagonizing early innate immune pathways; these include interferon (IFN) production and signaling, protein kinase R (PKR), and oligoadenylate synthetase...

Alternative Titles

Full title

MERS-CoV endoribonuclease and accessory proteins jointly evade host innate immunity during infection of lung and nasal epithelial cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2612228392

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2612228392

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.12.20.473564