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Single-nuclei isoform RNA sequencing reveals combination patterns of transcript elements across huma...

Single-nuclei isoform RNA sequencing reveals combination patterns of transcript elements across huma...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2615378988

Single-nuclei isoform RNA sequencing reveals combination patterns of transcript elements across human brain cell types

About this item

Full title

Single-nuclei isoform RNA sequencing reveals combination patterns of transcript elements across human brain cell types

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-12

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Single-nuclei RNA-Seq is being widely employed to investigate cell types, especially of human brain and other frozen samples. In contrast to single-cell approaches, however, the majority of single-nuclei RNA counts originate from partially processed RNA leading to intronic cDNAs, thus hindering the investigation of complete isoforms. Here, using mi...

Alternative Titles

Full title

Single-nuclei isoform RNA sequencing reveals combination patterns of transcript elements across human brain cell types

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2615378988

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2615378988

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.12.29.474385