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Human red blood cells express the RNA sensor TLR7 and bind viral RNA

Human red blood cells express the RNA sensor TLR7 and bind viral RNA

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2616140902

Human red blood cells express the RNA sensor TLR7 and bind viral RNA

About this item

Full title

Human red blood cells express the RNA sensor TLR7 and bind viral RNA

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2022-01

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Red blood cells (RBCs) express the nucleic acid-sensing toll-like receptor 9 (TLR9) and bind CpG-containing DNA. However, whether human RBCs express other nucleic acid-sensing TLRs and bind RNA is unknown. Here we show that human RBCs express the RNA sensor, TLR7. TLR7 is present on the red cell membrane and associates with the RBC membrane protein...

Alternative Titles

Full title

Human red blood cells express the RNA sensor TLR7 and bind viral RNA

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2616140902

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2616140902

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2022.01.01.474694