Cardiomyocytes disrupt pyrimidine biosynthesis in nonmyocytes to regulate heart repair
Cardiomyocytes disrupt pyrimidine biosynthesis in nonmyocytes to regulate heart repair
About this item
Full title
Author / Creator
Li, Shen , Yokota, Tomohiro , Wang, Ping , Hoeve, Johanna Ten , Ma, Feiyang , Le, Thuc M , Abt, Evan R , Zhou, Yonggang , Wu, Rimao , Nanthavongdouangsy, Maxine , Rodriguez, Abraham , Wang, Yijie , Lin, Yen-Ju , Muranaka, Hayato , Sharpley, Mark , Braddock, Demetrios T , MacRae, Vicky E , Banerjee, Utpal , Chiou, Pei-Yu , Seldin, Marcus , Huang, Dian , Teitell, Michael , Gertsman, Ilya , Jung, Michael , Bensinger, Steven J , Damoiseaux, Robert , Faull, Kym , Pellegrini, Matteo , Lusis, Aldons J , Graeber, Thomas G , Radu, Caius G and Deb, Arjun
Publisher
Ann Arbor: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
Ann Arbor: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Various populations of cells are recruited to the heart after cardiac injury, but little is known about whether cardiomyocytes directly regulate heart repair. Using a murine model of ischemic cardiac injury, we demonstrate that cardiomyocytes play a pivotal role in heart repair by regulating nucleotide metabolism and fates of nonmyocytes. Cardiac i...
Alternative Titles
Full title
Cardiomyocytes disrupt pyrimidine biosynthesis in nonmyocytes to regulate heart repair
Authors, Artists and Contributors
Author / Creator
Yokota, Tomohiro
Wang, Ping
Hoeve, Johanna Ten
Ma, Feiyang
Le, Thuc M
Abt, Evan R
Zhou, Yonggang
Wu, Rimao
Nanthavongdouangsy, Maxine
Rodriguez, Abraham
Wang, Yijie
Lin, Yen-Ju
Muranaka, Hayato
Sharpley, Mark
Braddock, Demetrios T
MacRae, Vicky E
Banerjee, Utpal
Chiou, Pei-Yu
Seldin, Marcus
Huang, Dian
Teitell, Michael
Gertsman, Ilya
Jung, Michael
Bensinger, Steven J
Damoiseaux, Robert
Faull, Kym
Pellegrini, Matteo
Lusis, Aldons J
Graeber, Thomas G
Radu, Caius G
Deb, Arjun
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2622818901
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2622818901
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCM49711
