A phenotype-based forward genetic screen identifies Dnajb6 as a sick sinus syndrome gene
A phenotype-based forward genetic screen identifies Dnajb6 as a sick sinus syndrome gene
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Author / Creator
Ding, Yonghe , Lang, Di , Yan, Jianhua , Bu, Haisong , Li, Hongsong , Jiao, Kunli , Yang, Jingchun , Le, Tai , Clark, Karl , Ekker, Stephen C , Cao, Hung , Zhang, Yuji , Li, Yigang , Glukhov, Alexey V and Xu, Xiaolei C
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Scope and Contents
Contents
Sick sinus syndrome (SSS) is a group of heart rhythm disorders caused by malfunction of the sinus node, the heart's primary pacemaker. Partially owing to its aging-associated phenotypic manifestation and low expressivity, molecular mechanisms of SSS remain difficult to decipher. Here, we aim to develop a phenotype-based forward genetic approach in...
Alternative Titles
Full title
A phenotype-based forward genetic screen identifies Dnajb6 as a sick sinus syndrome gene
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Record Identifier
TN_cdi_proquest_journals_2622858874
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2622858874
Other Identifiers
ISSN
2692-8205
E-ISSN
2692-8205
DOI
10.1101/2022.01.25.477752
