Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical...
Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability
About this item
Full title
Author / Creator
Shi, Wei , Wang, Lingshu , Zhou, Tongqing , Sastry, Mallika , Yang, Eun Sung , Zhang, Yi , Chen, Man , Chen, Xuejun , Choe, Misook , Creanga, Adrian , Leung, Kwan , Olia, Adam S , Pegu, Amarendra , Rawi, Reda , Shen, Chen-Hsiang , Stancofski, Erik-Stephane D , Talana, Chloe Adrienna , Teng, I-Ting , Wang, Shuishu , Corbett, Kizzmekia S , Tsybovsky, Yaroslav , Mascola, John R and Kwong, Peter D
Publisher
United States: Cold Spring Harbor Laboratory Press
Journal title
Language
English
Formats
Publication information
Publisher
United States: Cold Spring Harbor Laboratory Press
Subjects
More information
Scope and Contents
Contents
Immunization with SARS-CoV-2 spike elicits diverse antibodies, but can any of these neutralize broadly? Here, we report the isolation and characterization of antibody WS6, from a mouse immunized with mRNA encoding the SARS-CoV-2 spike. WS6 bound diverse beta-coronavirus spikes and neutralized SARS-CoV-2 variants, SARS-CoV, and related sarbecoviruse...
Alternative Titles
Full title
Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability
Authors, Artists and Contributors
Author / Creator
Wang, Lingshu
Zhou, Tongqing
Sastry, Mallika
Yang, Eun Sung
Zhang, Yi
Chen, Man
Chen, Xuejun
Choe, Misook
Creanga, Adrian
Leung, Kwan
Olia, Adam S
Pegu, Amarendra
Rawi, Reda
Shen, Chen-Hsiang
Stancofski, Erik-Stephane D
Talana, Chloe Adrienna
Teng, I-Ting
Wang, Shuishu
Corbett, Kizzmekia S
Tsybovsky, Yaroslav
Mascola, John R
Kwong, Peter D
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2622859005
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2622859005
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2022.01.25.477770
