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Subclonal evolution and expansion of THY1-positive cells is associated with recurrence in glioblasto...

Subclonal evolution and expansion of THY1-positive cells is associated with recurrence in glioblasto...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2624803781

Subclonal evolution and expansion of THY1-positive cells is associated with recurrence in glioblastoma

About this item

Full title

Subclonal evolution and expansion of THY1-positive cells is associated with recurrence in glioblastoma

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2022-02

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Glioblastoma (GBM) is a lethal disease characterized by treatment resistance and recurrence. To investigate the mechanisms that drive treatment resistance in GBM, we developed a longitudinal in vivo recurrence model utilizing patient-derived GBM explants to produce paired specimens pre- and post-recurrence following temozolomide(TMZ) and radiation(...

Alternative Titles

Full title

Subclonal evolution and expansion of THY1-positive cells is associated with recurrence in glioblastoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2624803781

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2624803781

Other Identifiers

DOI

10.1101/2021.09.10.459454