50S subunit recognition and modification by the Mycobacterium tuberculosis ribosomal RNA methyltrans...
50S subunit recognition and modification by the Mycobacterium tuberculosis ribosomal RNA methyltransferase TlyA
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Changes in bacterial ribosomal RNA methylation status can alter the activity of diverse groups of ribosome-targeting antibiotics. These modifications are typically incorporated by a single methyltransferase that acts on one nucleotide target and rRNA methylation directly prevents drug binding, thereby conferring drug resistance. Loss of intrinsic m...
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Full title
50S subunit recognition and modification by the Mycobacterium tuberculosis ribosomal RNA methyltransferase TlyA
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TN_cdi_proquest_journals_2627874871
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2627874871
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E-ISSN
2692-8205
DOI
10.1101/2021.11.11.467980
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https://www.proquest.com/docview/2627874871?pq-origsite=primo&accountid=13902