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Efficacy, durability, and safety of intravitreal faricimab up to every 16 weeks for neovascular age-...

Efficacy, durability, and safety of intravitreal faricimab up to every 16 weeks for neovascular age-...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2629784632

Efficacy, durability, and safety of intravitreal faricimab up to every 16 weeks for neovascular age-related macular degeneration (TENAYA and LUCERNE): two randomised, double-masked, phase 3, non-inferiority trials

About this item

Full title

Efficacy, durability, and safety of intravitreal faricimab up to every 16 weeks for neovascular age-related macular degeneration (TENAYA and LUCERNE): two randomised, double-masked, phase 3, non-inferiority trials

Author / Creator

Heier, Jeffrey S , Patel, Vaibhavi , Viola, Francesco , Adan Civera, Alfredo , Agostini, Hansjurgen , Almony, Arghavan , Antoszyk, Andrew , Awh, Carl C. , Brown, Jamin , Budzinskaya, Maria , Buffet, Sylvia , Byon, Iksoo , Calzada, Jorge , Carneiro, Angela , Chao, Daniel , Chen, Shih-Jen , Cheung, Gemmy , Chexal, Saradha , Chittum, Mark , Cornut, Pierre Loic , Dessouki, Amr , Dolz, Rosa , Eldem, Bora , Escobar, Joan Josep , Falk, Naomi , Feiner, Leonard , Fernandez Vega, Alvaro , Figueroa, Marta , Fine, Howard , Franco, Pablo , Fraser-Bell, Samantha , Furno Sola, Federico , Giunta, Michel , Gomez Ulla, Francisco , Gupta, Sunil , Guthoff, Rainer , Guymer, Robyn , Hampton, Robert , Hayashi, Ken , Heier, Jeffrey , Howard, James , Hu, Allen , Imaizumi, Hiroko , Javey, Golnaz , Javid, Cameron , Klein-Mascia, Kendra , Kobayashi, Namie , Kodjikian, Laurent , Kulikov, Alexey , Kwong, Henry , Kwun, Robert , Lai, Timothy , Lai, Chi-Chun , Lalonde, Laurent , Lanzetta, Paolo , Lee, ji Eun , Lindsell, Lucas , London, Nikolas , Lotery, Andrew , Lozano Rechy, David , Margherio, Alan , Masse, Helene , Michels, Mark , Mohamed, Quresh , Montero, Javier , Morori-Katz, Haia , Murata, Toshinori , Muzyka-Wozniak, Maria , Oleksy, Piotr , Patel, Apurva , Pauleikhoff, Daniel , Pearce, Ian , Qureshi, Jawad , Razavi, Hessam , Reilly, Gayatri , Saedon, Habiba , Saeed, Usman , Sararols, Laura , Schadlu, Ramin , Schlottmann, Patricio , Sekiryu, Tetsuju , Seres, András , Sheidow, Thomas , Sikorski, Bartosz , Singerman, Lawrence , Souied, Eric , Steinmetz, Robert , Stoller, Glenn , Taleb, Alexandre , Tran, Khoi , Vajas, Attila , Virgili, Gianni , Weber, Pamela , Wells, John A. , Williams, Thomas , Yilmaz, Gursel , Yiu, Glenn , Yoneda, Ai , Yoon, Young Hee , Zeolite, Carlos and TENAYA and LUCERNE Investigators

Publisher

England: Elsevier Ltd

Journal title

The Lancet (British edition), 2022-02, Vol.399 (10326), p.729-740

Language

English

Formats

Publication information

Publisher

England: Elsevier Ltd

More information

Scope and Contents

Contents

Faricimab is a bispecific antibody that acts through dual inhibition of both angiopoietin-2 and vascular endothelial growth factor A. We report primary results of two phase 3 trials evaluating intravitreal faricimab with extension up to every 16 weeks for neovascular age-related macular degeneration (nAMD).
TENAYA and LUCERNE were randomised, do...

Alternative Titles

Full title

Efficacy, durability, and safety of intravitreal faricimab up to every 16 weeks for neovascular age-related macular degeneration (TENAYA and LUCERNE): two randomised, double-masked, phase 3, non-inferiority trials

Authors, Artists and Contributors

Author / Creator

Heier, Jeffrey S
Patel, Vaibhavi
Viola, Francesco
Adan Civera, Alfredo
Agostini, Hansjurgen
Almony, Arghavan
Antoszyk, Andrew
Awh, Carl C.
Brown, Jamin
Budzinskaya, Maria
Buffet, Sylvia
Byon, Iksoo
Calzada, Jorge
Carneiro, Angela
Chao, Daniel
Chen, Shih-Jen
Cheung, Gemmy
Chexal, Saradha
Chittum, Mark
Cornut, Pierre Loic
Dessouki, Amr
Dolz, Rosa
Eldem, Bora
Escobar, Joan Josep
Falk, Naomi
Feiner, Leonard
Fernandez Vega, Alvaro
Figueroa, Marta
Fine, Howard
Franco, Pablo
Fraser-Bell, Samantha
Furno Sola, Federico
Giunta, Michel
Gomez Ulla, Francisco
Gupta, Sunil
Guthoff, Rainer
Guymer, Robyn
Hampton, Robert
Hayashi, Ken
Heier, Jeffrey
Howard, James
Hu, Allen
Imaizumi, Hiroko
Javey, Golnaz
Javid, Cameron
Klein-Mascia, Kendra
Kobayashi, Namie
Kodjikian, Laurent
Kulikov, Alexey
Kwong, Henry
Kwun, Robert
Lai, Timothy
Lai, Chi-Chun
Lalonde, Laurent
Lanzetta, Paolo
Lee, ji Eun
Lindsell, Lucas
London, Nikolas
Lotery, Andrew
Lozano Rechy, David
Margherio, Alan
Masse, Helene
Michels, Mark
Mohamed, Quresh
Montero, Javier
Morori-Katz, Haia
Murata, Toshinori
Muzyka-Wozniak, Maria
Oleksy, Piotr
Patel, Apurva
Pauleikhoff, Daniel
Pearce, Ian
Qureshi, Jawad
Razavi, Hessam
Reilly, Gayatri
Saedon, Habiba
Saeed, Usman
Sararols, Laura
Schadlu, Ramin
Schlottmann, Patricio
Sekiryu, Tetsuju
Seres, András
Sheidow, Thomas
Sikorski, Bartosz
Singerman, Lawrence
Souied, Eric
Steinmetz, Robert
Stoller, Glenn
Taleb, Alexandre
Tran, Khoi
Vajas, Attila
Virgili, Gianni
Weber, Pamela
Wells, John A.
Williams, Thomas
Yilmaz, Gursel
Yiu, Glenn
Yoneda, Ai
Yoon, Young Hee
Zeolite, Carlos
TENAYA and LUCERNE Investigators

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2629784632

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2629784632

Other Identifiers

ISSN

0140-6736

E-ISSN

1474-547X

DOI

10.1016/S0140-6736(22)00010-1

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