Novel tacrine-based acetylcholinesterase inhibitors as potential agents for the treatment of Alzheim...
Novel tacrine-based acetylcholinesterase inhibitors as potential agents for the treatment of Alzheimer’s disease: Quinolotacrine hybrids
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Full title
Author / Creator
Publisher
Cham: Springer International Publishing
Journal title
Language
English
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Publication information
Publisher
Cham: Springer International Publishing
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Scope and Contents
Contents
A new series of quinolotacrine hybrids including cyclopenta- and cyclohexa-quinolotacrine derivatives were designed, synthesized, and assessed as anti-cholinesterase (ChE) agents. The designed derivatives indicated higher inhibitory effect on the acetylcholinesterase (AChE) with IC
50
values of 0.285–100 µM compared to butyrylcholinesterase (...
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Full title
Novel tacrine-based acetylcholinesterase inhibitors as potential agents for the treatment of Alzheimer’s disease: Quinolotacrine hybrids
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Record Identifier
TN_cdi_proquest_journals_2634282085
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2634282085
Other Identifiers
ISSN
1381-1991
E-ISSN
1573-501X
DOI
10.1007/s11030-021-10307-2
