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Stereotactic body radiotherapy plus pembrolizumab and trametinib versus stereotactic body radiothera...

Stereotactic body radiotherapy plus pembrolizumab and trametinib versus stereotactic body radiothera...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2634513478

Stereotactic body radiotherapy plus pembrolizumab and trametinib versus stereotactic body radiotherapy plus gemcitabine for locally recurrent pancreatic cancer after surgical resection: an open-label, randomised, controlled, phase 2 trial

About this item

Full title

Stereotactic body radiotherapy plus pembrolizumab and trametinib versus stereotactic body radiotherapy plus gemcitabine for locally recurrent pancreatic cancer after surgical resection: an open-label, randomised, controlled, phase 2 trial

Publisher

England: Elsevier Ltd

Journal title

The lancet oncology, 2022-03, Vol.23 (3), p.e105-e115

Language

English

Formats

Publication information

Publisher

England: Elsevier Ltd

More information

Scope and Contents

Contents

SummaryBackgroundThere is paucity of investigations into immunotherapy or targeted therapy for postoperative locally recurrent pancreatic cancer. We aimed to assess the efficacy of stereotactic body radiotherapy (SBRT) plus pembrolizumab and trametinib in these patients. MethodsIn this open-label, randomised, controlled, phase 2 study, participants...

Alternative Titles

Full title

Stereotactic body radiotherapy plus pembrolizumab and trametinib versus stereotactic body radiotherapy plus gemcitabine for locally recurrent pancreatic cancer after surgical resection: an open-label, randomised, controlled, phase 2 trial

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2634513478

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2634513478

Other Identifiers

ISSN

1470-2045

E-ISSN

1474-5488

DOI

10.1016/S1470-2045(22)00066-3

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