Dual Immunotherapy in Advanced Non-small Cell Lung Cancer: the Progress and Clinical Application
Dual Immunotherapy in Advanced Non-small Cell Lung Cancer: the Progress and Clinical Application
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Tianjin: Chinese Anti-Cancer Association Chinese Antituberculosis Association
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Chinese
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Tianjin: Chinese Anti-Cancer Association Chinese Antituberculosis Association
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近年来,程序性死亡受体1(programmed death protein-1, PD-1)/程序性死亡配体1(programmed death-ligand 1, PD-L1)抑制剂单药、PD-1抑制剂联合化疗日益广泛地用于非小细胞肺癌(non-small cell lung cancer, NSCLC)的一线治疗,但PD-L1低表达的患者治疗反应和生存获益有限,现有治疗方案尚不能完全满足真实世界患者的临床需求。因此,研究者们仍在探索新的有效或者高效的治疗方案,以求进一步提高NSCLC不同人群的疗效和生存预后。双免疫联合治疗,如PD-1抑制剂和细胞毒性T淋巴细胞相关抗原4(cytotoxic T lymphocyte associated antigen-4, CTLA-4)抑制剂联合在多...
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Dual Immunotherapy in Advanced Non-small Cell Lung Cancer: the Progress and Clinical Application
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TN_cdi_proquest_journals_2636370511
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2636370511
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ISSN
1009-3419
E-ISSN
1999-6187
DOI
10.3779/j.issn.1009-3419.2021.102.48