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Extracellular prostaglandins E1 and E2 and inflammatory cytokines are regulated by the senescence pr...

Extracellular prostaglandins E1 and E2 and inflammatory cytokines are regulated by the senescence pr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2638174342

Extracellular prostaglandins E1 and E2 and inflammatory cytokines are regulated by the senescence program in potentially premalignant oral keratinocytes

About this item

Full title

Extracellular prostaglandins E1 and E2 and inflammatory cytokines are regulated by the senescence program in potentially premalignant oral keratinocytes

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2022-03

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Potentially pre-malignant lesions (PPOLs) are composed of keratinocytes that are either mortal (MPPOL) or immortal (IPPOL) in vitro. We report here that MPPOL, but not generally IPPOL keratinocytes upregulate various extracellular tumor promoting cytokines (interleukins 6 and 8) and prostaglandins E1 (ePGE1) and E2 (ePGE2) relative to normal oral k...

Alternative Titles

Full title

Extracellular prostaglandins E1 and E2 and inflammatory cytokines are regulated by the senescence program in potentially premalignant oral keratinocytes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2638174342

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2638174342

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2022.03.10.483769