Interferon-induced lysosomal membrane permeabilization and death cause cDC1-deserts in tumors
Interferon-induced lysosomal membrane permeabilization and death cause cDC1-deserts in tumors
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Author / Creator
Aerakis, Emmanouil , Chatzigeorgiou, Arsenios , Maria-Michaela Alvanou , Matthaiakaki-Panagiotaki, Maria , Angelidis, Ilias , Koumadorakis, Dimitris , Galaras, Alexandros , Hatzis, Pantelis , Kerdidani, Dimitra , Makridakis, Manousos , Vlahou, Antonia , Malissen, Bernard , Henri, Sandrine , Merad, Miriam and Tsoumakidou, Maria
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
T cell immunity requires antigen capture by conventional dendritic cells (cDCs), digestion and transfer to draining lymph nodes for presentation to antigen-inexperienced T cells. cDCs type I excel as cancer-antigen presenting cells, due to their ability to phagocytose, slowly digest apoptotic cancer cells and translocate cancer antigens to the cyto...
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Full title
Interferon-induced lysosomal membrane permeabilization and death cause cDC1-deserts in tumors
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TN_cdi_proquest_journals_2638853036
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2638853036
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E-ISSN
2692-8205
DOI
10.1101/2022.03.14.484263
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https://www.proquest.com/docview/2638853036?pq-origsite=primo&accountid=13902
