Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms...
Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model
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Author / Creator
Peter Ac Wing , Prange-Barczynska, Maria , Cross, Amy , Crotta, Stefania , Rubio, Claudia Orbegozo , Cheng, Xiaotong , Harris, James M , Zhuang, Xiaodong , Johnson, Rachel L , Ryan, Kathryn A , Hall, Yper , Carroll, Miles W , Issa, Fadi , Balfe, Peter , Wack, Andreas , Bishop, Tammie , Salguero, Francisco J and Mckeating, Jane A
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Understanding the host pathways that define susceptibility to SARS-CoV-2 infection and disease are essential for the design of new therapies. Oxygen levels in the microenvironment define the transcriptional landscape, however the influence of hypoxia on virus replication and disease in animal models is not well understood. In this study, we identif...
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Full title
Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model
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TN_cdi_proquest_journals_2639116154
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2639116154
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E-ISSN
2692-8205
DOI
10.1101/2022.03.15.484379
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https://www.proquest.com/docview/2639116154?pq-origsite=primo&accountid=13902
