Nuclear export of adenovirus E4orf6 protein is necessary for its ability to antagonize apoptotic act...
Nuclear export of adenovirus E4orf6 protein is necessary for its ability to antagonize apoptotic activity of BH3-only proteins
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The adenovirus E4orf6 is a viral oncoprotein known to cooperate with the E1A gene product in transforming primary murine cells. It has been shown to inhibit the apoptotic activities of p53 and p73 through direct binding to these proteins. Here, we demonstrate that the adenovirus E4orf6 protein inhibits apoptosis mediated by BNIP3 and Bik, which are...
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Nuclear export of adenovirus E4orf6 protein is necessary for its ability to antagonize apoptotic activity of BH3-only proteins
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TN_cdi_proquest_journals_2641331902
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2641331902
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1206743
