CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB surviv...
CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway
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Author / Creator
Ma, S , Lee, T K , Zheng, B-J , Chan, K W and Guan, X-Y
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The recent discovery of cancer stem cells (CSCs) has played a pivotal role in changing our view of carcinogenesis and chemotherapy. Based on this concept, CSCs are responsible for the formation and growth of neoplastic tissue and are naturally resistant to chemotherapy, explaining why traditional chemotherapies can initially shrink a tumor but fail...
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Full title
CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway
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TN_cdi_proquest_journals_2641371469
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2641371469
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1210811