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CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB surviv...

CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB surviv...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2641371469

CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway

About this item

Full title

CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2008-03, Vol.27 (12), p.1749-1758

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The recent discovery of cancer stem cells (CSCs) has played a pivotal role in changing our view of carcinogenesis and chemotherapy. Based on this concept, CSCs are responsible for the formation and growth of neoplastic tissue and are naturally resistant to chemotherapy, explaining why traditional chemotherapies can initially shrink a tumor but fail...

Alternative Titles

Full title

CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2641371469

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2641371469

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/sj.onc.1210811

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