Arginine-dependent hypusination of the eukaryotic translation initiation factor (eIF)5A drives eryth...
Arginine-dependent hypusination of the eukaryotic translation initiation factor (eIF)5A drives erythroid lineage differentiation
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Author / Creator
Gonzalez-Menendez, Pedro , Phadke, Ira , Olive, Meagan E , Mcgraw, Kathy L , Platon, Jessica , Papoin, Julien , Yan, Hongxia , Daumur, Marie , Franciane, Paul , Mirmira, Raghavendra , Joly, Axel , Galtier, Jeremy , Narla, Anupama , Cartron, Guillaume , Dardalhon, Valérie , Zimmermann, Valérie S , Sitbon, Marc , Dever, Thomas E , Mohandas, Narla , Da Costa, Lydie , Udeshi, Namrata D , Blanc, Lionel , Kinet, Sandrina and Taylor, Naomi
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Scope and Contents
Contents
Metabolic programs contribute to hematopoietic stem and progenitor cell (HSPC) fate but it is not known whether the metabolic regulation of protein synthesis controls HSPC differentiation. We discovered that SLC7A1/CAT1-dependent arginine uptake and its catabolism to spermidine control the erythroid specification of HSPCs via activation of eukaryot...
Alternative Titles
Full title
Arginine-dependent hypusination of the eukaryotic translation initiation factor (eIF)5A drives erythroid lineage differentiation
Authors, Artists and Contributors
Author / Creator
Phadke, Ira
Olive, Meagan E
Mcgraw, Kathy L
Platon, Jessica
Papoin, Julien
Yan, Hongxia
Daumur, Marie
Franciane, Paul
Mirmira, Raghavendra
Joly, Axel
Galtier, Jeremy
Narla, Anupama
Cartron, Guillaume
Dardalhon, Valérie
Zimmermann, Valérie S
Sitbon, Marc
Dever, Thomas E
Mohandas, Narla
Da Costa, Lydie
Udeshi, Namrata D
Blanc, Lionel
Kinet, Sandrina
Taylor, Naomi
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2641679374
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2641679374
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2022.03.21.485053
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https://www.proquest.com/docview/2641679374?pq-origsite=primo&accountid=13902