Single Nucleus RNA Sequencing of Pre-Malignant Liver Reveals Disease-Associated Hepatocyte State wit...
Single Nucleus RNA Sequencing of Pre-Malignant Liver Reveals Disease-Associated Hepatocyte State with HCC Prognostic Potential
About this item
Full title
Author / Creator
Carlessi, Rodrigo , Denisenko, Elena , Boslem, Ebru , Koehn-Gaone, Julia , Main, Nathan , Nur Dianah Ba Bakar , Shirolkar, Gayatri D , Jones, Matthew , Poppe, Daniel , Dwyer, Benjamin J , Jackaman, Connie , Tjiam, M Christian , Lister, Ryan , Karin, Michael , Fallowfield, Jonathan A , Kendall, Timothy James , bes, Stuart J , Olynyk, John K , Yeoh, George , rest, Alistair R R , Ramm, Grant A , Febbraio, Mark A and Tirnitz-Parker, Janina E E
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
Formats
Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Subjects
More information
Scope and Contents
Contents
Current approaches to stage chronic liver diseases have limited utility to directly predict liver cancer risk. Here, we employed single nucleus RNA sequencing (snRNA-seq) to characterize the cellular microenvironment of healthy and chronically injured pre-malignant livers using two distinct mouse models. Analysis of 40,748 hepatic nuclei unraveled...
Alternative Titles
Full title
Single Nucleus RNA Sequencing of Pre-Malignant Liver Reveals Disease-Associated Hepatocyte State with HCC Prognostic Potential
Authors, Artists and Contributors
Author / Creator
Denisenko, Elena
Boslem, Ebru
Koehn-Gaone, Julia
Main, Nathan
Nur Dianah Ba Bakar
Shirolkar, Gayatri D
Jones, Matthew
Poppe, Daniel
Dwyer, Benjamin J
Jackaman, Connie
Tjiam, M Christian
Lister, Ryan
Karin, Michael
Fallowfield, Jonathan A
Kendall, Timothy James
bes, Stuart J
Olynyk, John K
Yeoh, George
rest, Alistair R R
Ramm, Grant A
Febbraio, Mark A
Tirnitz-Parker, Janina E E
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2643844522
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2643844522
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2022.03.25.485695
How to access this item
https://www.proquest.com/docview/2643844522?pq-origsite=primo&accountid=13902
