A Distinct Chromatin State Drives Therapeutic Resistance in Invasive Lobular Breast Cancer
A Distinct Chromatin State Drives Therapeutic Resistance in Invasive Lobular Breast Cancer
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Author / Creator
Nardone, Agostina , Qui, Xintao , Feiglin, Ariel , Fu, Xiaoyong , Spisak, Sandor , Feit, Avery , Gabriella Cohen Feit , Xie, Yingtian , Font-Tello, Alba , Guarducci, Cristina , Francisco Hermida Prado , Sudeepa Syamala , Lim, Klothilda , Pun, Matthew , Macintosh Cornwell , Liu, Weihan , Ors, Aysegul , Mohammed, Hisham , Brock, Jane Elizabeth , Freedman, Matthew L , Schiff, Rachel , Winer, Eric , Long, Henry W , Otto Metzger Filho and Jeselsohn, Rinath
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Scope and Contents
Contents
Most invasive lobular breast cancers (ILC) are of the luminal A subtype and strongly hormone receptor positive. Yet, they are relatively resistant to tamoxifen and are associated with inferior long-term outcomes compared to invasive ductal cancers (IDC). In this study, we sought to gain mechanistic insights into these clinical findings that are not...
Alternative Titles
Full title
A Distinct Chromatin State Drives Therapeutic Resistance in Invasive Lobular Breast Cancer
Authors, Artists and Contributors
Author / Creator
Qui, Xintao
Feiglin, Ariel
Fu, Xiaoyong
Spisak, Sandor
Feit, Avery
Gabriella Cohen Feit
Xie, Yingtian
Font-Tello, Alba
Guarducci, Cristina
Francisco Hermida Prado
Sudeepa Syamala
Lim, Klothilda
Pun, Matthew
Macintosh Cornwell
Liu, Weihan
Ors, Aysegul
Mohammed, Hisham
Brock, Jane Elizabeth
Freedman, Matthew L
Schiff, Rachel
Winer, Eric
Long, Henry W
Otto Metzger Filho
Jeselsohn, Rinath
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2645320483
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2645320483
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E-ISSN
2692-8205
DOI
10.1101/2022.03.29.486217
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https://www.proquest.com/docview/2645320483?pq-origsite=primo&accountid=13902