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Cobalt chloride and low oxygen tension trigger differentiation of acute myeloid leukemic cells: poss...

Cobalt chloride and low oxygen tension trigger differentiation of acute myeloid leukemic cells: poss...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2645713080

Cobalt chloride and low oxygen tension trigger differentiation of acute myeloid leukemic cells: possible mediation of hypoxia-inducible factor-1α

About this item

Full title

Cobalt chloride and low oxygen tension trigger differentiation of acute myeloid leukemic cells: possible mediation of hypoxia-inducible factor-1α

Publisher

London: Nature Publishing

Journal title

Leukemia, 2003-11, Vol.17 (11), p.2065-2073

Language

English

Formats

Publication information

Publisher

London: Nature Publishing

More information

Scope and Contents

Contents

Cellular and systemic O2 concentrations are tightly regulated to maintain delicate oxygen homeostasis. Although the roles of hypoxia in solid tumors have been widely studied, few studies were reported regarding the possible effects of hypoxia on leukemic cells. Here, we showed for the first time that low concentrations of cobalt chloride (CoCl2), a...

Alternative Titles

Full title

Cobalt chloride and low oxygen tension trigger differentiation of acute myeloid leukemic cells: possible mediation of hypoxia-inducible factor-1α

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2645713080

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2645713080

Other Identifiers

ISSN

0887-6924

E-ISSN

1476-5551

DOI

10.1038/sj.leu.2403141

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