Altered miRNA and gene expression in acute myeloid leukemia with complex karyotype identify networks...
Altered miRNA and gene expression in acute myeloid leukemia with complex karyotype identify networks of prognostic relevance
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Author / Creator
Rücker, F G , Russ, A C , Cocciardi, S , Kett, H , Schlenk, R F , Botzenhardt, U , Langer, C , Krauter, J , Fröhling, S , Schlegelberger, B , Ganser, A , Lichter, P , Zenz, T , Döhner, H , Döhner, K and Bullinger, L
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Recently, the p53-miR-34a network has been identified to have an important role in tumorigenesis. As in acute myeloid leukemia with complex karyotype (CK-AML)
TP53
alterations are the most common known molecular lesion, we further analyzed the p53-miR-34a axis in a large cohort of CK-AML with known
TP53
status (
TP53
altered
,<...
Alternative Titles
Full title
Altered miRNA and gene expression in acute myeloid leukemia with complex karyotype identify networks of prognostic relevance
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Record Identifier
TN_cdi_proquest_journals_2645732342
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2645732342
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ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/leu.2012.208