A functional polymorphism of the cytochrome P450 1A2 (CYP1A2) gene: association with tardive dyskine...
A functional polymorphism of the cytochrome P450 1A2 (CYP1A2) gene: association with tardive dyskinesia in schizophrenia
About this item
Full title
Author / Creator
Basile, V S , Özdemir, V , Masellis, M , Walker, M L , Meltzer, H Y , Lieberman, J A , Potkin, S G , Alva, G , Kalow, W , Macciardi, F M and Kennedy, J L
Publisher
Basingstoke: Nature Publishing Group
Journal title
Language
English
Formats
Publication information
Publisher
Basingstoke: Nature Publishing Group
Subjects
More information
Scope and Contents
Contents
Tardive dyskinesia (TD) is a common and potentially irreversible side effect associated with long-term treatment with typical antipsychotics. Approximately, 80% or more of patients with schizophrenia are smokers. Smoking is a potent inducer of the CYP1A2 enzyme, and is known to cause a significant decrease in plasma concentrations of some antipsych...
Alternative Titles
Full title
A functional polymorphism of the cytochrome P450 1A2 (CYP1A2) gene: association with tardive dyskinesia in schizophrenia
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2645753460
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2645753460
Other Identifiers
ISSN
1359-4184
E-ISSN
1476-5578
DOI
10.1038/sj.mp.4000736
