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An open protocol for modeling T Cell Clonotype repertoires using TCRβ CDR3 sequences

An open protocol for modeling T Cell Clonotype repertoires using TCRβ CDR3 sequences

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2646019775

An open protocol for modeling T Cell Clonotype repertoires using TCRβ CDR3 sequences

About this item

Full title

An open protocol for modeling T Cell Clonotype repertoires using TCRβ CDR3 sequences

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2022-04

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

T cell receptor (TCR) repertoires can be profiled using next generation sequencing (NGS) to monitor dynamical changes in response to disease and other perturbations. Several strategies for profiling TCRs have been recently developed with different benefits and drawbacks. Genomic DNA-based bulk sequencing, however, remains the most cost-effective me...

Alternative Titles

Full title

An open protocol for modeling T Cell Clonotype repertoires using TCRβ CDR3 sequences

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2646019775

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2646019775

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2022.03.30.486449