An open protocol for modeling T Cell Clonotype repertoires using TCRβ CDR3 sequences
An open protocol for modeling T Cell Clonotype repertoires using TCRβ CDR3 sequences
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
T cell receptor (TCR) repertoires can be profiled using next generation sequencing (NGS) to monitor dynamical changes in response to disease and other perturbations. Several strategies for profiling TCRs have been recently developed with different benefits and drawbacks. Genomic DNA-based bulk sequencing, however, remains the most cost-effective me...
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Full title
An open protocol for modeling T Cell Clonotype repertoires using TCRβ CDR3 sequences
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TN_cdi_proquest_journals_2646019775
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2646019775
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E-ISSN
2692-8205
DOI
10.1101/2022.03.30.486449
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https://www.proquest.com/docview/2646019775?pq-origsite=primo&accountid=13902