HNF4A-AS1-encoded small peptide promotes self-renewal and aggressiveness of neuroblastoma stem cells...
HNF4A-AS1-encoded small peptide promotes self-renewal and aggressiveness of neuroblastoma stem cells via eEF1A1-repressed SMAD4 transactivation
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Song, Huajie , Wang, Jianqun , Wang, Xiaojing , Yuan, Boling , Li, Dan , Hu, Anpei , Guo, Yanhua , Cai, Shuang , Jin, Shikai , Zhou, Yi , Li, Qilan , Chen, Guo , Gao, Haiyang , Zheng, Liduan and Tong, Qiangsong
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Cancer stem cells play crucial roles in tumorigenesis and aggressiveness, while regulatory mechanisms in neuroblastoma (NB), a pediatric extracranial malignancy with highest incidence, are still unknown. Herein, a small 51-amino acid peptide (sPEP1) encoded by hepatocyte nuclear factor 4 alpha antisense RNA 1 (
HNF4A-AS1
) was identified in t...
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Full title
HNF4A-AS1-encoded small peptide promotes self-renewal and aggressiveness of neuroblastoma stem cells via eEF1A1-repressed SMAD4 transactivation
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TN_cdi_proquest_journals_2653413690
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2653413690
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ISSN
0950-9232,1476-5594
E-ISSN
1476-5594
DOI
10.1038/s41388-022-02271-4
