Discoidin Domain Receptor 2 orchestrates melanoma resistance combining phenotype switching and proli...
Discoidin Domain Receptor 2 orchestrates melanoma resistance combining phenotype switching and proliferation
About this item
Full title
Author / Creator
Sala, Margaux , Allain, Nathalie , Moreau, Mélanie , Jabouille, Arnaud , Henriet, Elodie , Abou-Hammoud, Aya , Uguen, Arnaud , Di-Tommaso, Sylvaine , Dourthe, Cyril , Raymond, Anne-Aurélie , Dupuy, Jean-William , Gerard, Emilie , Dugot-Senant, Nathalie , Rousseau, Benoit , Merlio, Jean-Phillipe , Pham-Ledart, Anne , Vergier, Béatrice , Tartare-Deckert, Sophie , Moreau, Violaine and Saltel, Frédéric
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Combined therapy with anti-BRAF plus anti-MEK is currently used as first-line treatment of patients with metastatic melanomas harboring the somatic
BRAF
V600E mutation. However, the main issue with targeted therapy is the acquisition of tumor cell resistance. In a majority of resistant melanoma cells, the resistant process consists in epithel...
Alternative Titles
Full title
Discoidin Domain Receptor 2 orchestrates melanoma resistance combining phenotype switching and proliferation
Authors, Artists and Contributors
Author / Creator
Allain, Nathalie
Moreau, Mélanie
Jabouille, Arnaud
Henriet, Elodie
Abou-Hammoud, Aya
Uguen, Arnaud
Di-Tommaso, Sylvaine
Dourthe, Cyril
Raymond, Anne-Aurélie
Dupuy, Jean-William
Gerard, Emilie
Dugot-Senant, Nathalie
Rousseau, Benoit
Merlio, Jean-Phillipe
Pham-Ledart, Anne
Vergier, Béatrice
Tartare-Deckert, Sophie
Moreau, Violaine
Saltel, Frédéric
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2656977390
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2656977390
Other Identifiers
ISSN
0950-9232,1476-5594
E-ISSN
1476-5594
DOI
10.1038/s41388-022-02266-1