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Loss of CD24 promotes radiation- and chemo-resistance by inducing stemness properties associated wit...

Loss of CD24 promotes radiation- and chemo-resistance by inducing stemness properties associated wit...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2659820730

Loss of CD24 promotes radiation- and chemo-resistance by inducing stemness properties associated with a hybrid E/M state in breast cancer cells

About this item

Full title

Loss of CD24 promotes radiation- and chemo-resistance by inducing stemness properties associated with a hybrid E/M state in breast cancer cells

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2022-05

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

There is compelling evidence that cancer stem cells (CSCs) play an essential role in failure of conventional antitumor therapy. In breast cancer, CD24-/low/CD44+ phenotype as well as a high aldehyde dehydrogenase activity (ALDH+) are widely associated with CSC subtypes. Furthermore, CD24-/low/CD44+ pattern is also characteristic of the mesenchymal...

Alternative Titles

Full title

Loss of CD24 promotes radiation- and chemo-resistance by inducing stemness properties associated with a hybrid E/M state in breast cancer cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2659820730

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2659820730

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2022.05.05.490732