A transistor-like pH-sensitive nanodetergent for selective cancer therapy
A transistor-like pH-sensitive nanodetergent for selective cancer therapy
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London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Plasma membrane rupture is a promising strategy for drug-resistant cancer treatment, but its application is limited by the low tumour selectivity of membranolytic molecules. Here we report the design of ‘proton transistor’ nanodetergents that can convert the subtle pH perturbation signals of tumour tissues into sharp transition signals of membranol...
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A transistor-like pH-sensitive nanodetergent for selective cancer therapy
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TN_cdi_proquest_journals_2666124676
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2666124676
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ISSN
1748-3387
E-ISSN
1748-3395
DOI
10.1038/s41565-022-01085-5
